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The use of oral sprays allows for B12 to be delivered directly into the mouth, to permeate the highly vascular tissue of the mucous membrane lining

Biol Reproduction (2021) 104(6):11813

Other skincare products contain ingredients such as tranexamic acid, kojic acid, niacinamide, azelaic acid, and cysteamine, which all work to inhibit the melanin production process to reduce increased skin pigmentation